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Scientist Martha Chase and Alfred Hershey While DNA had been known to biologists since 1869, [ 2 ] many scientists still assumed at the time that proteins carried the information for inheritance because DNA appeared to be an inert molecule, and, since it is located in the nucleus, its role was considered to be phosphorus storage.
Martha Cowles Chase (November 30, 1927 – August 8, 2003), also known as Martha C. Epstein, [1] was an American geneticist who in 1952, with Alfred Hershey, experimentally helped to confirm that DNA rather than protein is the genetic material of life.
Hershey left Washington University in 1950 for the Department of Genetics of the Carnegie Institution of Washington, a predecessor of Cold Spring Harbor Laboratory. Two years later, he and Martha Chase would conduct the famous Hershey–Chase, or "Waring Blender" experiment . [ 4 ]
Hershey, [7] described retrospectively the circumstances leading to the experiment using phage that he performed with his research assistant, Martha Chase, in 1952, later known as the Hershey–Chase experiment. [8]
Experiments conducted in 1952 by Alfred Hershey and Martha Chase demonstrated how the DNA of viruses is injected into the bacterial cells, while most of the viral proteins remain outside. [1] [2] The injected DNA molecules cause the bacterial cells to produce more viral DNA and proteins. These discoveries supported that DNA, rather than ...
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In 1952, Alfred Hershey and Martha Chase confirmed that the genetic material of the bacteriophage, the virus which infects bacteria, is made up of DNA [4] (see Hershey–Chase experiment). In 1953, James Watson and Francis Crick discovered the double helical structure of the DNA molecule based on the discoveries made by Rosalind Franklin. [5]
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