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  2. Sotatercept - Wikipedia

    en.wikipedia.org/wiki/Sotatercept

    In the United States, sotatercept is indicated for the treatment of adults with pulmonary arterial hypertension (PAH, WHO Group 1). [6] [10]In the European Union, sotatercept, in combination with other pulmonary arterial hypertension therapies, is indicated for the treatment of pulmonary arterial hypertension in adults with WHO Functional Class (FC) II to III, to improve exercise capacity.

  3. In March 2024, the FDA approved Winrevair (sotatercept-csrk), for injection, 45mg, 60mg for adults with PAH to increase exercise capacity, improve WHO functional class, and reduce the risk of ...

  4. Pulmonary arterial hypertension - Wikipedia

    en.wikipedia.org/.../Pulmonary_arterial_hypertension

    A pulmonary artery wedge pressure being less than 15 mmHg (also measured by right heart catheterization) excludes post-capillary bed (in the veins distal to the capillary bed) pulmonary hypertension. Pulmonary arterial hypertension is a subgroup of pulmonary hypertension and is categorized as World Health Organization as group 1. [3]

  5. Milrinone - Wikipedia

    en.wikipedia.org/wiki/Milrinone

    Milrinone is a commonly used therapy for severe pulmonary arterial hypertension (PAH), [14] often in combination with other medications such as sildenafil. [15] Targeting PDE3 with optimal doses and timing, milrinone prevents allergic inflammation in HDM-driven models of allergic airway inflammation.

  6. Why Is Merck Stock Trading Higher On Monday? - AOL

    www.aol.com/finance/why-merck-stock-trading...

    In March, the FDA approved Winrevair for injection for adults with pulmonary arterial hypertension (PAH) to increase exercise capacity, improve WHO functional class (FC), and reduce the risk of ...

  7. Pulmonary hypertension - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_hypertension

    Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the arteries of the lungs. [7] Symptoms include shortness of breath, fainting, tiredness, chest pain, swelling of the legs, and a fast heartbeat. [7] [1] The condition may make it difficult to exercise. [7] Onset is typically gradual. [8]