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[11] [13] These "targets" should generally be as unlike any proteins or parts of proteins in humans as possible, to reduce the likelihood of side effects and toxicity. [8] The targets should also be common across many strains of a virus, or even among different species of virus in the same family, so a single drug will have broad effectiveness.
COVID-19: Shionogi: 3C-like protease inhibitor Entecavir: HIV NRTI 2005 Etravirine (Intelence) [8] HIV NNRTI 2008 Famciclovir: Herpes Zoster: Guanosine analogue 1994 Fomivirsen: AIDS Anti-sense oligonucleotide: Anti-sense FDA-licensed in 1998; Withdrawn in EU (2002), US (2006) Fosamprenavir: HIV ViiV Healthcare: Amprenavir pro-drug: 2003 (FDA ...
Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox , and shingles . [ 6 ] Other uses include, prevention of cytomegalovirus infections following transplant, and severe complications of Epstein–Barr virus infection.
People initiating nPEP treatment typically receive a 28-day starter pack rather than a 3–7 day starter pack, to facilitate strong medication adherence. [20] They should also be counseled on unpleasant side effects including malaise, fatigue, diarrhea, headache, nausea, vomiting, and insomnia, depending on the medication administered. [25] [29]
This means staying home if you test positive for the virus—though isolation guidelines have changed quite a bit since SARS-CoV-2, the virus that causes illness with Covid-19, first emerged.
Individuals may experience distress from quarantine, travel restrictions, side effects of treatment, or fear of the infection itself. To address these concerns, the National Health Commission of China published a national guideline for psychological crisis intervention on 27 January 2020.
Longer-term effects of COVID-19 have become a prevalent aspect of the disease itself. These symptoms can be referred to by many names including post-COVID-19 syndrome, long COVID, and long haulers syndrome. An overall definition of post-COVID conditions (PCC) can be described as a range of symptoms that can last for weeks or months. [83]
The Health Protection (Coronavirus) Regulations 2020 (SI 2020/129) was a set of regulations that came into effect in England on 10 February 2020 as a statutory instrument made under the Public Health (Control of Disease) Act 1984. The regulations were revoked on 25 March 2020.