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Adenine (/ ˈ æ d ɪ n iː n /, / ˈ æ d ɪ n ɪ n /) (symbol A or Ade) is a purine nucleotide base. It is one of the nucleobases in the nucleic acids, DNA and RNA. The shape of adenine is complementary to either thymine in DNA or uracil in RNA. In cells adenine, as an independent molecule, is rare.
The molecule consists of an adenine attached to a ribose via a β-N 9-glycosidic bond. Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA ), which are essential for all life on Earth.
Speakers of non-rhotic accents, as in much of Australia, England, New Zealand, and Wales, will pronounce the second syllable [fəd], those with the father–bother merger, as in much of the US and Canada, will pronounce the first syllable [ˈɑːks], and those with the cot–caught merger but without the father–bother merger, as in Scotland ...
This nucleotide contains the five-carbon sugar deoxyribose (at center), a nucleobase called adenine (upper right), and one phosphate group (left). The deoxyribose sugar joined only to the nitrogenous base forms a Deoxyribonucleoside called deoxyadenosine, whereas the whole structure along with the phosphate group is a nucleotide, a constituent of DNA with the name deoxyadenosine monophosphate.
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Nucleobases such as adenine, guanine, xanthine, hypoxanthine, purine, 2,6-diaminopurine, and 6,8-diaminopurine may have formed in outer space as well as on earth. [ 7 ] [ 8 ] [ 9 ] The origin of the term base reflects these compounds' chemical properties in acid–base reactions , but those properties are not especially important for ...