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A generalized tonic–clonic seizure, commonly known as a grand mal seizure or GTCS, [1] is a type of generalized seizure that produces bilateral, convulsive tonic and clonic muscle contractions. Tonic–clonic seizures are the seizure type most commonly associated with epilepsy and seizures in general and the most common seizure associated ...
Tonic-clonic seizures occur with a contraction of the limbs followed by their extension and arching of the back which lasts 10–30 seconds (the tonic phase). A cry may be heard due to contraction of the chest muscles, followed by a shaking of the limbs in unison (clonic phase). Tonic seizures produce constant contractions of the muscles.
Earlier age of seizure onset is correlated with a higher risk of cognitive impairment. Progressive myoclonus epilepsy (PME) is a group of diseases characterized by myoclonus, epileptic seizures, tonic–clonic seizures, and other serious symptoms such as trouble walking or speaking. These rare disorders often get worse over time and can be fatal.
A seizure is a sudden change in behavior, movement or consciousness due to abnormal electrical activity in the brain. [3] [6] Seizures can look different in different people.. It can be uncontrolled shaking of the whole body (tonic-clonic seizures) or a person spacing out for a few seconds (absence seizure
Levetiracetam is effective for treatment of generalized tonic-clonic epilepsy. [18] It has been approved in the United States as add-on treatment for myoclonic , and tonic-clonic seizures. [ 4 ] Levetiracetam has been approved in the European Union as a monotherapy treatment for epilepsy in the case of partial seizures or as an adjunctive ...
Tonic-clonic seizures: seizures with repetitive sequences of stiffening and jerking of the extremities. Myoclonic seizures: seizures with rapid, brief contractions of muscles. Atonic seizures: seizures with a sudden loss of muscle tone, often resulting in sudden collapse. These are also called drop seizures or astatic seizures.