Search results
Results From The WOW.Com Content Network
The periosteum consists of an outer fibrous layer, and an inner cambium layer (or osteogenic layer). The fibrous layer is of dense irregular connective tissue , containing fibroblasts , while the cambium layer is highly cellular containing progenitor cells that develop into osteoblasts . [ 3 ]
A perichondrium layer surrounding the cartilage forms the periosteum, which generates osteogenic cells that then go on to make a collar that encircles the outside of the bone and remodels the medullary cavity on the inside. The nutrient artery enters via the nutrient foramen from a small opening in the diaphysis.
The first isolation technique by microdissection method was originally described by Fell et al. [37] using chick limb bones which were separated into periosteum and remaining parts. She obtained cells which possessed osteogenic characteristics from cultured tissue using chick limb bones which were separated into periosteum and remaining parts.
The outer surface of a bone is lined by a thin layer of connective tissue that is very similar in morphology and function to endosteum. It is called the periosteum , or the periosteal surface. During bone growth , the width of the bone increases as osteoblasts lay new bone tissue at the periosteum.
Osteoblasts are generally present on the outer layer of bone, just beneath the periosteum. Attachment of the osteoclast to the osteon begins the process. The osteoclast then induces an infolding of its cell membrane and secretes collagenase and other enzymes important in the resorption process.
The periosteum is formed around the trabeculae by differentiating mesenchymal cells. The primary center of ossification is the area where bone growth occurs between the periosteum and the bone. Osteogenic cells that originate from the periosteum increase appositional growth and a bone collar is formed.
Sharpey's fibres (bone fibres, or perforating fibres) are a matrix of connective tissue consisting of bundles of strong predominantly type I collagen fibres connecting periosteum to bone. They are part of the outer fibrous layer of periosteum, entering into the outer circumferential and interstitial lamellae of bone tissue.
This newly formed bone can be called "periosteal bone" as it originates from the transformed periosteum. However, considering its developmental pathway, it could be classified as "intramembranous bone". [8] After the formation of the periosteum, chondrocytes in the primary center of ossification begin to grow (hypertrophy).