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An electron transport chain (ETC [1]) is a series of protein complexes and other molecules which transfer electrons from electron donors to electron acceptors via redox reactions (both reduction and oxidation occurring simultaneously) and couples this electron transfer with the transfer of protons (H + ions) across a membrane.
The chain of redox reactions driving the flow of electrons through the electron transport chain, from electron donors such as NADH to electron acceptors such as oxygen and hydrogen (protons), is an exergonic process – it releases energy, whereas the synthesis of ATP is an endergonic process, which requires an input of energy.
The electron transport chain is responsible for establishing a pH and electrochemical gradient that facilitates the production of ATP through the pumping of protons. The gradient also provides control of the concentration of ions such as Ca 2+ driven by the mitochondrial membrane potential. [ 1 ]
Detailed diagram of the electron transport chain in mitochondria. In the electron transport chain, complex I (CI) catalyzes the reduction of ubiquinone (UQ) to ubiquinol (UQH 2) by the transfer of two electrons from reduced nicotinamide adenine dinucleotide (NADH) which translocates four protons from the mitochondrial matrix to the IMS: [18
From there the NADH and FADH go into the NADH reductase, which produces the enzyme. The NADH pulls the enzyme's electrons to send through the electron transport chain. The electron transport chain pulls H + ions through the chain. From the electron transport chain, the released hydrogen ions make ADP for an result of 32 ATP.
These electrons enter the electron transport chain of the mitochondria via reduction equivalents to generate ATP. The shuttle system is required because the mitochondrial inner membrane is impermeable to NADH , the primary reducing equivalent of the electron transport chain.
NADH is oxidized into NAD +, H + ions, and electrons by an enzyme. FADH 2 is also oxidized into H + ions, electrons, and FAD.As those electrons travel farther through the electron transport chain in the inner membrane, energy is gradually released and used to pump the hydrogen ions from the splitting of NADH and FADH 2 into the space between the inner membrane and the outer membrane (called ...
This is an electron transport chain (ETC). Electron transport chains often produce energy in the form of a transmembrane electrochemical potential gradient. The gradient can be used to transport molecules across membranes. Its energy can be used to produce ATP or to do useful work, for instance mechanical work of a rotating bacterial flagella.