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Over two million prescriptions for paroxetine were written for children or adolescents in the US in 2002. [29]Funded by SmithKline Beecham, the acute phase of study 329 was an eight-week, double-blind, randomized clinical trial conducted in 12 university or hospital psychiatric departments in the United States and Canada between 1994 and 1997.
The depression is multifactorial and has been on the increase due to societal pressure, genetic association and increase in use of drugs (Zhang et al. 2016) [full citation needed]. incorporation of nursing in management of depression may seem important in that nursing hold a pivotal role in health care delivery where they are they are the ...
They may recommend adjusting your dosage or gradually reducing the dosage of your current antidepressant, then using a new form of antidepressant therapy after a tapering period. Learn More About ...
Paroxetine, sold under the brand name Paxil among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [7] used to treat major depressive disorder, obsessive–compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
[187] [188] Fluvoxamine is an agonist of the σ 1 receptor, while sertraline is an antagonist of the σ 1 receptor, and paroxetine does not significantly interact with the σ 1 receptor. [187] [188] None of the SSRIs have significant affinity for the σ 2 receptor. [187] [188] Fluvoxamine has by far the strongest activity of the SSRIs at the σ ...
The UK National Institute for Health and Care Excellence (NICE)'s 2022 guidelines indicate that antidepressants should not be routinely used for the initial treatment of mild depression, "unless that is the person's preference". [29] The guidelines recommended that antidepressant treatment be considered:
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