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The primary treatment for bipolar disorder consists of medications called mood stabilizers, which are used to prevent or control episodes of mania or depression. Medications from several classes have mood stabilizing activity.
Antipsychotic medications are effective for short-term treatment of bipolar manic episodes and appear to be superior to lithium and anticonvulsants for this purpose. [68] Atypical antipsychotics are also indicated for bipolar depression refractory to treatment with mood stabilizers. [120]
Although bipolar disorder is a chronic mental health condition, treatments are available to help manage it. This includes medication, psychotherapy, and lifestyle strategies.
Lithium Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar).
At least five atypical antipsychotics (lumateperone, [48] cariprazine, [49] lurasidone, [50] olanzapine, [51] and quetiapine [52]) have also been found to possess efficacy in the treatment of bipolar depression as a monotherapy, whereas only olanzapine [53] and quetiapine [54] [55] have been proven to be effective broad-spectrum (i.e., against ...
In 1970, lithium was approved by the United States Food and Drug Administration (FDA) for the treatment of bipolar disorder, which remains its primary use in the US. [ 5 ] [ 17 ] It is sometimes used when other treatments are not effective in a number of other conditions, including major depression , [ 18 ] schizophrenia , disorders of impulse ...
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