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The human virome is a part of human bodies and will not always cause harm. [23] Many latent and asymptomatic viruses are present in the human body all the time. Viruses infect all life forms; therefore the bacterial, plant, and animal cells and material in the gut also carry viruses. [6]
Although bacteriophages cannot infect human cells, they are found in abundance in the human virome. [7] Phageome research in humans has largely focused on the gut, however it is also being investigated in other areas like the skin, [8] blood, [9] and mouth. [10] The composition of phages that make up a healthy human gut phageome is currently ...
The gut microbiota comprises all microorganisms that reside along the gastrointestinal tract, including commensal, symbiotic and pathogenic organisms. FMT is the transfer of fecal material containing bacteria and natural antibacterials from a healthy individual into a diseased recipient.
Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. [ 1 ] [ 2 ] The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota .
Phage therapy has many potential applications in human medicine as well as dentistry, veterinary science, and agriculture. [20] If the target host of a phage therapy treatment is not an animal, the term "biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy". [9]
In the 2000s, the Rohwer lab sequenced viromes from seawater, [9] [10] marine sediments, [11] adult human stool, [12] infant human stool, [13] soil, [14] and blood. [15] This group also performed the first RNA virome with collaborators from the Genomic Institute of Singapore. [ 16 ]