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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Differences between Contrave and GLP-1 drugs like Ozempic. ... While Contrave has no direct benefits for diabetes, Nadolsky said GLP-1s can improve pancreatic insulin secretion and glucagon ...
Regular physical activity can help accelerate weight loss, improve metabolism and enhance the benefits of weight loss pills. Aim for 150 minutes per week (or about a half-hour five days a week).
[8] [14] Naltrexone, as naltrexone/bupropion (brand name Contrave), is also used to treat obesity. [15] It is on the World Health Organization's List of Essential Medicines. [16] In 2021, it was the 254th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [17] [18]
SGLT2 inhibitors cause the loss of 60–100 grams (2.1–3.5 oz) glucose in the urine each day and are associated with a modest, sustained weight loss of 1.5–2 kilograms (3.3–4.4 lb) in people with type 2 diabetes. The weight loss is less than expected due to compensatory increases in energy intake, but is additive when combined with GLP-1 ...
This leads the pancreas to produce more insulin, which helps lower blood sugar levels and promote weight loss. GLP-1 drugs for weight loss and type 2 diabetes include dulaglutide, liraglutide, and ...
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