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The anterolateral system (ALS) is an ascending bundle of fibers in the spinal cord, carried in three main pathways or tracts. [1] The tracts convey pain, [6] temperature (protopathic sensation), and crude touch from the periphery to the brain. The most important of these is the spinothalamic tract. [2]
Cordotomy is performed as for patients with severe intractable pain, usually but not always due to cancer.Being irreversible and relatively invasive, cordotomy is used exclusively for pain where treatment to level 3 of the World Health Organization pain ladder (i.e., use of major opiates such as morphine) has proved inadequate.
The tract transmits slow nociceptive/pain information (but thermal, and crude touch information as well) from the spinal cord to reticular formation which in turn relays the information to the thalamus via reticulothalamic fibers as well as to other parts of the brain (as opposed to the spinothalamic tract - the direct pathway of the ...
Descending tracts are pathways by which motor signals are sent from upper motor neurons in the brain to lower motor neurons which then directly innervate muscle to produce movement. The anterior corticospinal tract is usually small, varying inversely in size with the lateral corticospinal tract , which is the main part of the corticospinal tract .
Diffuse noxious inhibitory controls (DNIC) or conditioned pain modulation (CPM) refers to an endogenous pain modulatory pathway which has often been described as "pain inhibits pain". [1] It occurs when response from a painful stimulus is inhibited by another, often spatially distant, noxious stimulus.
The spinocerebellar tracts are nerve tracts originating in the spinal cord and terminating in the same side (ipsilateral) of the cerebellum.The two main tracts are the dorsal spinocerebellar tract, and the ventral spinocerebellar tract.
The course of GVA fibers from organs in the pelvis, in general, depends on the organ's position relative to the pelvic pain line.An organ, or part of an organ, in the pelvis is said to be "above the pelvic pain line" if it is in contact with the peritoneum, except in the case of the large intestine, where the pelvic pain line is said to be located in the middle of the sigmoid colon. [6]
[citation needed] These carry pain and temperature sensation. These fibers cross through the anterior white commissure to form the anterolateral system in the lateral funiculus. The medial division of the dorsal root contains myelinated fibres of larger diameter [citation needed].