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V d is the volume of distribution (L); typically body weight (kg) multiplied by 0.71 L/kg for men and 0.58 L/kg for women [32] [33] although estimation using TBW is more accurate. [34] A standard drink, defined by the WHO as 10 grams of pure alcohol, [35] is the most frequently used measure in many countries. Examples: A 80 kg man drinks 20 ...
Since one in about every 6,400 hydrogen atoms is deuterium, a 50-kilogram (110 lb) human containing 32 kilograms (71 lb) of body water would normally contain enough deuterium (about 1.1 grams or 0.039 ounces) to make 5.5 grams (0.19 oz) of pure heavy water, so roughly this dose is required to double the amount of deuterium in the body.
In living organisms, the pH of various Body fluids, cellular compartments, and organs is tightly regulated to maintain a state of acid-base balance known as acid–base homeostasis. Acidosis , defined by blood pH below 7.35, is the most common disorder of acid–base homeostasis and occurs when there is an excess of acid in the body.
Water is an inorganic compound with the chemical formula H 2 O.It is a transparent, tasteless, odorless, [c] and nearly colorless chemical substance.It is the main constituent of Earth's hydrosphere and the fluids of all known living organisms (in which it acts as a solvent [20]).
It is the eighth most abundant element in the human body by weight, [101] about equal in abundance to potassium, and slightly greater than sodium and chlorine. [102] A 70 kg (150 lb) human body contains about 140 grams (4.9 oz) of sulfur. [103]
A study of humans exposed in 2.5 hour sessions demonstrated significant negative effects on cognitive abilities at concentrations as low as 0.1% (1000 ppm) CO 2 likely due to CO 2 induced increases in cerebral blood flow. [52] Another study observed a decline in basic activity level and information usage at 1000 ppm, when compared to 500 ppm. [53]
Tin is the 49th most abundant element in Earth's crust, representing 2 ppm compared with 75 ppm for zinc, 50 ppm for copper, and 14 ppm for lead. [ 56 ] Tin does not occur as the native element but must be extracted from various ores.
100 ppm IDLH (NIOSH): immediately dangerous to life and health (the level that interferes with the ability to escape) 0.00047 ppm or 0.47 ppb is the odor threshold, the point at which 50% of a human panel can detect the presence of an odor without being able to identify it. [71] 10–20 ppm is the borderline concentration for eye irritation.