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Chloral hydrate is a geminal diol with the formula Cl 3 C−CH(OH) 2. It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was replaced by safer and more effective alternatives but it remained in usage in the United States until at least the 1970s. [ 4 ]
Ethchlorvynol is a member of the class of sedative-hypnotic carbinols, which includes methylparafynol and tert-amyl alcohol.It is not a benzodiazepine, carbamate, or barbituric acid derivative, and its molecular structure is considerably simpler.
Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.
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Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and tension headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles.
Following a rupture in supply 2014–2015 [3] the product returned to French pharmacies in June 2016 with the same composition, minus chloral hydrate, now banned, and with the indication "mouthwash" («bain de bouche») removed. [4] Among the new uses of the reformulation is endorsement of the Synthol gel as an umbilical cord antiseptic. [5]