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  2. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Other off-label uses include cancer pain, hot sweats, certain psychiatric disorders, nicotine dependence, opioid withdrawal, migraine headaches, and restless leg syndrome. Colchicine (Colcrys) for pericarditis: colchicine is indicated for the treatment and prevention of gout, though it is also generally considered first-line treatment for acute ...

  3. Off-label use - Wikipedia

    en.wikipedia.org/wiki/Off-label_use

    Up to one-fifth of all drugs are prescribed off-label and amongst psychiatric drugs, off-label use rises to 31%. [3] Among use of antipsychotic medications in the United States, a shift occurred from typical agents in 1995 (84% of all antipsychotic visits) to atypical agents by 2008 (93%). Atypical use has grown far beyond substitution for the ...

  4. Acetylcysteine - Wikipedia

    en.wikipedia.org/wiki/Acetylcysteine

    Acetylcysteine is extensively liver metabolized, CYP450 minimal, urine excretion is 22–30% with a half-life of 5.6 hours in adults and 11 hours in newborns. [medical citation needed] Acetylcysteine is the N-acetyl derivative of the amino acid L-cysteine, and is a precursor in the formation of the antioxidant glutathione in the body.

  5. Atypical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Atypical_antipsychotic

    The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...

  6. List of off-label promotion pharmaceutical settlements

    en.wikipedia.org/wiki/List_of_off-label...

    Allegations of off-label promotion, however, centered on the off-label promotion of several cancer drugs. [6] The drug Temodar , which was approved by the Food and Drug Administration (FDA) in 1999 for treatment of a specific type of brain tumor, was allegedly being promoted as a treatment for other types of brain cancer for which it had not ...

  7. Antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic

    Some studies have found decreased life expectancy associated with the use of antipsychotics, and argued that more studies are needed. [137] [138] Antipsychotics may also increase the risk of early death in individuals with dementia. [139] Antipsychotics typically worsen symptoms in people with depersonalisation disorder. [140]