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Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. [1] [2] When initiated by the clinician, it is known as deprescribing. [3]
[5] In patients with chronic heart failure, the plasma level of bisoprolol is higher and the half-life is longer than in healthy subjects when compared across studies. There is a lack of evidence directly comparing bisoprolol pharmacokinetics between healthy subjects and chronic heart failure subjects. [50] [51]
[14] [15] [16] Bisoprolol, carvedilol, and sustained-release metoprolol are specifically indicated as adjuncts to standard ACE inhibitor and diuretic therapy in congestive heart failure, although at doses typically much lower than those indicated for other conditions. Beta blockers are only indicated in cases of compensated, stable congestive ...
The study analyzed records of more than 125,000 adults who began taking the GLP-1 drugs liraglutide, semaglutide, or tirzepatide between January 2018 and December 2023.
Weight loss drugs Wegovy and Ozempic can lead to significant weight loss. But when you stop taking the drugs, the weight can come back.
Even a small amount of weight loss, such as 5-10% of your total body weight, can bring your blood pressure down, stabilize your blood sugar, improve your blood cholesterol and give you more energy.”
Many prescription and legal nonprescription substances can also cause withdrawal symptoms when individuals stop consuming them, even if they were taken as directed by a physician. The route of administration, whether intravenous, intramuscular, oral, or otherwise can also play a role in determining the severity of withdrawal symptoms.
While these GLP-1 drugs are not recommended for short-term use, people stop taking them for a variety of reasons, including reaching their weight loss goals, severity of side effects, and cost.