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Cinchocaine (INN/BAN) or dibucaine is an amide local anesthetic. Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. [1] [2] It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine.
A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the front of the eyeball, the inside of the nose, ear or throat, the anus and the genital area. [1]
Some drugs may be legally classified as over-the-counter (i.e. no prescription is required), but may only be dispensed by a pharmacist after an assessment of the patient's needs or the provision of patient education. Regulations detailing the establishments where drugs may be sold, who is authorized to dispense them, and whether a prescription ...
Some experts are averse to over-the-counter antidepressants because the evidence for their effectiveness is weak compared to prescription medications and active ingredients vary among brands and ...
Some experts are averse to over-the-counter antidepressants because the evidence for their effectiveness is weak compared to prescription medications and active ingredients vary among brands and ...
The duration of such paralysis may last from hours to days. To identify susceptible individuals, the dibucaine number can be determined so as to alert the care team to the risks of use of butyrylcholinesterase substrates. Pestel et al. [6] measured 24,830 Dibucaine numbers over a period of four years in a European trial. Numbers below 30 ...