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Isotretinoin carries a high risk of causing severe birth defects if taken during pregnancy [5] (see Teratogenicity of isotretinoin) and the goals of the iPLEDGE REMS (risk evaluation and mitigation strategy) program are to prevent fetal exposure to isotretinoin and to inform prescribers, pharmacists, and patients about isotretinoin's serious ...
Medications during pregnancy must be carefully considered. Many types of drugs, medications, and even nutritional supplements can affect fetal development or cause complications. For over-the-counter and prescription medications, healthcare professionals can help weigh the potential risks and benefits of taking medication while pregnant and if ...
Accutane can be an effective solution for combating moderate to severe acne, but it comes with a unique set of instructions and some uncomfortable side effects. One reaction many Accutane users ...
REMS are also tailored to the medication (and subsequent side effects) it aims to surveil: For isotretinoin, the program focuses on preventing pregnancy, but for a medication like olanzapine (an ...
Isotretinoin is a teratogen highly likely to cause birth defects if taken by women during pregnancy or even a short time before conception. A few of the more common birth defects this drug can cause are hearing and visual impairment, missing or malformed earlobes, facial dysmorphism, and abnormalities in brain function.
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It can cause mild adverse effects such as photosensitivity, irritation, redness, dryness, itching, and burning, [7] and 1% to 10% of users [11] experience a brief sensation of warmth or stinging, as well as dry skin, peeling and redness during the first two to four weeks using the medication. [9] [12] These effects are considered mild and ...
AHFS/Drugs.com: UK Drug Information: Routes of administration: Topical gel: ... Some of the side effects are related to vitamin A toxicity. [1] Very common (≥ 1/10)