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60–95% (adults) [4] Herpes simplex, often known simply as herpes, is a viral infection caused by the herpes simplex virus. [5] Herpes infections are categorized by the area of the body that is infected. The two major types of herpes are oral herpes and genital herpes, though other forms also exist. Oral herpes involves the face or mouth.
Herpes virus DNA contains a gene for a protein called ICP4, which is an important transactivator of genes associated with lytic infection in HSV-1. [47] Elements surrounding the gene for ICP4 bind a protein known as the human neuronal protein neuronal restrictive silencing factor (NRSF) or human repressor element silencing transcription factor ...
Herpes simplex research. Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes. Examples of particular herpes research include drug development, vaccines and genome editing. HSV-1 and HSV-2 are commonly thought of as oral and genital ...
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [1] When symptoms do occur, they typically include small blisters that break open to form painful ulcers. [1] Flu-like symptoms, such as fever, aching, or swollen ...
The epidemiology of herpes simplex is of substantial epidemiologic and public health interest. Worldwide, the rate of infection with herpes simplex virus —counting both HSV-1 and HSV-2—is around 90%. [1] Although many people infected with HSV develop labial or genital lesions (herpes simplex), the majority are either undiagnosed or display ...
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A cold sore[a] is a type of herpes infection caused by the herpes simplex virus that affects primarily the lip. [1] Symptoms typically include a burning pain followed by small blisters or sores. [1] The first attack may also be accompanied by fever, sore throat, and enlarged lymph nodes. [1][9] The rash usually heals within ten days, but the ...
Human gammaherpesvirus 8. Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is Human gammaherpesvirus 8, or HHV-8 in short. [1] Like other herpesviruses, its informal names are used interchangeably with its formal ICTV name.