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Figure 1. Early Symptoms of HIV. The stages of HIV infection are acute infection (also known as primary infection), latency, and AIDS. Acute infection lasts for several weeks and may include symptoms such as fever, swollen lymph nodes, inflammation of the throat, rash, muscle pain, malaise, and mouth and esophageal sores. The latency stage ...
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...
Even with anti-retroviral treatment, over the long term HIV-infected people may experience neurocognitive disorders, [219] osteoporosis, [220] neuropathy, [221] cancers, [222] [223] nephropathy, [224] and cardiovascular disease. [174] Some conditions, such as lipodystrophy, may be caused both by HIV and its treatment. [174]
Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
Disease-specific drugs can also alleviate symptoms of AIDS and even cure specific AIDS-defining conditions in some cases. Medical treatment can reduce HIV infection in many cases to a survivable chronic condition. However, these advances do not constitute a cure, since current treatment regimens cannot eradicate latent HIV from the body.
Strong sales of medicines for HIV, the virus that causes AIDS, were one of the drivers behind the company's performance last year, generating 6.44 billion pounds ($8.13 billion) in annual sales.
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