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Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of each cerebral hemisphere of the brain. It has a distinctive, curved shape that has been likened to the sea-horse creature of Greek mythology , and the ram's horns of Amun in Egyptian mythology .
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system.
The hippocampal formation is a compound structure in the medial temporal lobe of the brain. It forms a c-shaped bulge on the floor of the inferior horn of the lateral ventricle . [ 1 ] Typically, the hippocampal formation is said to included the dentate gyrus , the hippocampus , and the subiculum . [ 2 ]
The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. ... The neurons in the polymorphic layer, including ...
The polymorphic layer is also the hilus of the dentate gyrus (CA4, the junction of the hippocampus and dentate gyrus). [15] [16] (In the hippocampus the outer layer is the molecular layer, the middle layer is the pyramidal layer, and the inner layer the stratum oriens.)
Pyramidal cells, or pyramidal neurons, are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal cells are the primary excitation units of the mammalian prefrontal cortex and the corticospinal tract .
The subicular complex receives input from CA1 and entorhinal cortical layer III pyramidal neurons and is the main output of the hippocampus proper.The pyramidal neurons send projections to the nucleus accumbens, septal nuclei, prefrontal cortex, lateral hypothalamus, nucleus reuniens, mammillary nuclei, entorhinal cortex and amygdala.
The entorhinal cortex (EC) is a structure in the brain located in the medial temporal lobe.The EC is composed of six distinct layers. The superficial (outer) layers, which include layers I through III, are mainly input layers that receive signals from other parts of the EC, but also project to hippocampal structures via the perforant path.