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Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. [1]
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel ).
One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5] Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). [6] [7]
Whether thrombophilia also increases the risk of arterial thrombosis (which is the underlying cause of heart attacks and strokes) is less well established. [ 2 ] [ 8 ] [ 9 ] However, more recent data suggest some forms of inherited thrombophilia are associated with increased risk for arterial ischemic stroke .
Low platelets and dysfunctional platelets, which cause heavier than average bruising and bleeding, are hallmarks of the disorder. [1] Individuals with RUNX1-FPD have a lifetime risk of being diagnosed with a hematologic malignancy of 35-45%. [2]
Research from Sweden has found a link between getting a tattoo of any size and an overall 21% higher risk of developing lymphoma, a type of blood cancer. Tattoos may increase blood cancer risk by ...
Pseudothrombocytopenia (PTCP) or spurious thrombocytopenia is an in-vitro sampling problem which may mislead the diagnosis towards the more critical condition of thrombocytopenia. The phenomenon may occur when the anticoagulant used while testing the blood sample causes clumping of platelets which mimics a low platelet count. [ 1 ]
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