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Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as atopic dermatitis (eczema), asthma and nasal polyps which result in chronic sinusitis. [6] [7] [8] [4] It is also used for the treatment of eosinophilic esophagitis, [9] prurigo nodularis [10] and ...
A newly approved drug for the treatment of atopic dermatitis could make a big difference to people with moderate-to-severe eczema. Image credit: Sascha Lotz/picture alliance via Getty Images.
Eczema, also known as atopic dermatitis, is an inflammatory skin condition that can cause itching, rashes and dry patches. The FDA's approval was based on three studies involving over 1,000 ...
Lebrikizumab, sold under the brand name Ebglyss is a humanized monoclonal antibody used for the treatment of atopic dermatitis (atopic eczema). [7] [8] It is an interleukin-13 antagonist. [7] It is given by subcutaneous injection. [7]
Crisaborole was developed by Anacor Pharmaceuticals for the topical treatment of psoriasis. [9] [6] [10] During preclinical and clinical development, crisaborole was called AN2728 and PF-06930164. [11] The drug was assumed to be potential $2bn-a-year blockbuster, when Pfizer acquired Anacor Pharmaceuticals. [12]
The company said the agency did not raise concerns about the clinical trial data, safety or label for lebrikizumab, a monoclonal antibody for treatment of atopic dermatitis, or eczema. The company ...
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