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[11] [12] This drug is now listed as a core medication for the treatment of leishmaniasis under the WHO Model List of Essential Medicines. [13] Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however, a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis.
Acute beryllium poisoning is an occupational disease. [1] Relevant occupations are those where beryllium is mined, processed or converted into metal alloys, or where machining of metals containing beryllium or recycling of scrap alloys occurs.
Beryllium poisoning is poisoning by the toxic effects of beryllium, or more usually its compounds. It takes two forms: Acute beryllium poisoning, usually as a result of exposure to soluble beryllium salts; Chronic beryllium disease (CBD) or berylliosis, usually as a result of long-term exposure to beryllium oxide usually caused by inhalation.
Berylliosis, or chronic beryllium disease (CBD), is a chronic allergic-type lung response and chronic lung disease caused by exposure to beryllium and its compounds, a form of beryllium poisoning. It is distinct from acute beryllium poisoning , which became rare following occupational exposure limits established around 1950. [ 1 ]
Dimercaprol has been used as an adjunct in the treatment of the acute encephalopathy of lead toxicity. It is a potentially toxic drug, and its use may be accompanied by multiple side effects. Although treatment with dimercaprol will increase the excretion of cadmium, there is a concomitant increase in renal cadmium concentration, so that its ...
Pyrimethamine, sold under the brand name Daraprim among others, is a medication used with leucovorin (leucovorin is used to decrease side effects of pyrimethamine; it does not have intrinsic anti-parasitic activity) to treat the parasitic diseases toxoplasmosis and cystoisosporiasis.
The drug is marketed either as a free base in an oily solution containing 192 mg in capsule form, or as clomethiazole edisylate syrup. Due to its high toxicity compared to similar drugs it is not recommended as a first-line treatment for any indication and is particularly dangerous to patients with an elevated risk for drug abuse such as those ...
The drug is a Narcotic in Schedule I of the Controlled Substances Act 1970 of the United States as drug number 9055. It is therefore subject to annual aggregate manufacturing quotas in the United States, and in 2014 the quota for desomorphine was 5 grams. [ 32 ]