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A phototoxic substance is a chemical compound which becomes toxic when exposed to light. Some medicines: tetracycline antibiotics, sulfonamides, amiodarone, quinolones, psoralen; Many cold pressed citrus essential oils such as bergamot oil [3] Some plant juices: parsley, lime, and Heracleum mantegazzianum
Photosensitive drug reaction secondary to medications may cause phototoxic, photoallergic, and lichenoid reactions, and photodistributed telangiectasias, as well as pseudoporphyria. [ 1 ] : 121 Drugs involved include naproxen and doxycycline .
Photodermatoses can be categorized into primary or secondary photodermatoses based on the cause of the reaction. Primary photodermatoses are immunology mediated or caused by chemical/drug exposure. An example of primary photodermatoses is Polymorphous light eruption. Polymorphous light eruption is the most common type of photodermatoses.
Phototoxins are toxins that can cause allergic reactions in particularly susceptible individuals and which can cause dangerous photosensitivity in a much broader range of subjects. Phototoxins are common in: a variety of plants (including food plants where they may be a biological defence): many citruses contain essential oils that are ...
Sometimes termed "photoaggravated", [18] and divided into two categories, phototoxic and photoallergic, PCD is the eczematous condition which is triggered by an interaction between an otherwise unharmful or less harmful substance on the skin and ultraviolet light (320–400 nm UVA) (ESCD 2006), therefore manifesting itself only in regions where ...
Photodermatitis, sometimes referred to as sun poisoning or photoallergy, is a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure.
Photosensitivity is the amount to which an object reacts upon receiving photons, especially visible light.In medicine, the term is principally used for abnormal reactions of the skin, and two types are distinguished, photoallergy and phototoxicity.
Sunlight, especially its ultraviolet radiation component, can cause increased or additional types of damage in predisposed individuals, such as those taking certain phototoxic drugs, or those with certain conditions associated with photosensitivity, including: Psoriasis [5] Atopic eczema [5] Mastocytosis; Mast cell activation syndrome ...