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Proton-pump inhibitor. Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump. [1] Proton-pump inhibitors have largely superseded the H 2 -receptor antagonists, a group of medications with ...
H 2 receptor antagonist. H. 2. receptor antagonist. H2 antagonists, sometimes referred to as H2RAs[1] and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H 2 receptors of the parietal cells in the stomach. This decreases the production of stomach acid. H 2 antagonists can be used in the ...
Cimetidine. Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. [1][9][10] It is mainly used in the treatment of heartburn and peptic ulcers. [1][10][11] Cimetidine is available as an over-the-counter formulation to prevent heartburn or acid indigestion, as ...
Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4]
Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. [3][4][5] Its usefulness in people infected by H. pylori is limited. [3] It is used by mouth (for upper GIT ulcers) and rectally (for ...
Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available. The group followed and has largely superseded another group of pharmaceuticals with similar effects, but a different mode of action, called H ...
Key:YREYEVIYCVEVJK-UHFFFAOYSA-N Y. (verify) Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid. [6] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production such as in Zollinger–Ellison syndrome. [6]
Ranitidine is an H 2 histamine receptor antagonist that works by blocking histamine, thus decreasing the amount of acid released by cells of the stomach. [12] Ranitidine was discovered in England in 1976 and came into commercial use in 1981. [26]
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