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Vasopressin. Human vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, [5] is a hormone synthesized from the AVP gene as a peptide prohormone in neurons in the hypothalamus, [6] and is converted to AVP. It then travels down the axon terminating in the posterior pituitary, and is released from vesicles ...
Desmopressin (1-deamino-8-D-arginine vasopressin) is a synthetic form of the normal human hormone arginine vasopressin (the antidiuretic hormone, or ADH), a peptide containing nine amino acids. Compared to vasopressin, desmopressin's first amino acid has been deaminated , and the arginine at the eighth position is in the dextro rather than the ...
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [13][14] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin. 1921 Research on the role of pancreas in ...
Nephrogenic diabetes insipidus, recently renamed arginine vasopressin resistance (AVP-R) and previously known as renal diabetes insipidus, is a form of diabetes insipidus primarily due to pathology of the kidney. This is in contrast to central or neurogenic diabetes insipidus, which is caused by insufficient levels of vasopressin (also called ...
Nephrogenic DI (NDI), also known as arginine vasopressin resistance (AVP-R), [5] occurs when the kidneys do not respond properly to vasopressin. [1] Dipsogenic DI is a result of excessive fluid intake due to damage to the hypothalamic thirst mechanism. [1] It occurs more often in those with certain psychiatric disorders or on certain ...
Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and is considered to be the main catabolic hormone of the body. [1] It is also used as a medication to treat a number of health conditions. Its effect is opposite to that of insulin, which lowers ...
Neurophysins. Neurophysins are carrier proteins which transport the hormones oxytocin and vasopressin to the posterior pituitary from the paraventricular and supraoptic nucleus of the hypothalamus, respectively. Inside the neurosecretory granules, the analogous neurophysin I and II form stabilizing complexes via covalent interactions. [1]
Ammonium chloride has also been used for forced acid diuresis, but it is a toxic compound. [6] Usually, however, this technique only produces a slight increase in the renal clearance of the drug. Forced acid diuresis is rarely done in practice, [ 7 ] but can be used to enhance the elimination of cocaine , amphetamine , quinine , quinidine ...