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  2. Belimumab - Wikipedia

    en.wikipedia.org/wiki/Belimumab

    Belimumab, sold under the brand name Benlysta, is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), [6] also known as B-lymphocyte stimulator (BLyS). [7] It is approved in the United States [8] and Canada, [9] and the European Union [5] to treat systemic lupus erythematosus and lupus nephritis. [10]

  3. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    Belimumab is a monoclonal antibody that inhibits B-cell activating factor and thereby inflammation. It was approved in 2019 by the US Food and Drug Administration to treat the musculoskeletal, cutaneous, and cardiac manifestations of children with cSLE who are over 5 years old. It is given intravenously to cSLE patients with active disease but ...

  4. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Hydroxychloroquine was approved by the FDA for lupus in 1955. [120] Some drugs approved for other diseases are used for SLE 'off-label'. In November 2010, an FDA advisory panel recommended approving belimumab (Benlysta) as a treatment for the pain and flare-ups common in lupus. The drug was approved by the FDA in March 2011. [121] [122]

  5. What to Know About How Lupus Affects Weight - AOL

    www.aol.com/know-lupus-affects-weight-163616391.html

    Certain medications for lupus may cause loss of appetite, diarrhea, or nausea that make it less appealing to eat and harder to keep food down, Patterson says, thereby contributing to weight loss ...

  6. After Living with Lupus Since She Was 16, Bride Gets ... - AOL

    www.aol.com/living-lupus-since-she-16-222500839.html

    According to the Lupus Foundation of America, there is "no single diagnostic test for systemic lupus," and that the tests are used to "detect physical changes or conditions in your body that can ...

  7. Biogen-UCB's lupus drug meets main goal of late-stage trial - AOL

    www.aol.com/news/biogen-ucbs-lupus-drug-meets...

    AstraZeneca's Saphnelo, approved in 2021, made $280 million in 2023 sales, while GSK's Benlysta, which first gained approval in 2011, brought in 1.35 billion euros ($1.50 billion) last year.

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