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Researchers say a person with a negative initial colonoscopy and no family history of colorectal cancer may not need to have another colonoscopy for 15 years instead of the traditional 10-year wait.
Taking family history into account, they found that after having a first negative colonoscopy, the risk of later having a colorectal cancer diagnosis or dying from the disease was about the same ...
Colonoscopy (/ ˌ k ɒ l ə ˈ n ɒ s k ə p i /) or coloscopy (/ k ə ˈ l ɒ s k ə p i /) [1] is a medical procedure involving the endoscopic examination of the large bowel (colon) and the distal portion of the small bowel.
Individuals at risk (due to family links or genetic testing) are usually offered routine monitoring of the intestinal tract every 1–3 years for life, from puberty for FAP and early adulthood for attenuated forms. Colon resection surgery is recommended if numerous colon polyps are found due to high risk of early death from colon cancer.
Affected individuals have an increased risk of colorectal cancer, precancerous colon polyps and an increased risk of several additional cancers. About 1–2 percent of the population possess a mutated copy of the MUTYH gene, and less than 1 percent of people have the MUTYH-associated polyposis syndrome.
“Colonoscopy can’t be effective if it’s not done, and the study did show a significant decrease in cancer incidence with colonoscopy, and this will ultimately lead to a decrease in deaths.”
Traditional serrated adenoma seen under microscopy with H&E stain, showing serrated crypts. SPS may occur with one of two phenotypes: distal or proximal. [6] The distal phenotype may demonstrate numerous small polyps in the distal colon and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). [6]
New research suggests that biological age — a measure of the body’s physiological state — could predict who is at higher risk for developing colon polyps, a key risk factor for colorectal ...