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Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).
The Josep Carreras Leukaemia Foundation is a private, charitable and non-profitable organization, founded by the tenor José Carreras following his recovery. Carreras founded the Foundation on July 14, 1988, with one single objective: that leukaemia will one day be 100% curable. He wanted to make a permanent testimony to science and society to ...
Aggressive NK-cell leukemia is a disease with an aggressive, systemic proliferation of natural killer cells (NK cells) and a rapidly declining clinical course. [ 1 ] [ 2 ] [ 3 ] It is also called aggressive NK-cell lymphoma .
UVA Cancer Center operates the LGL Leukemia Registry, the only national database and specimen bank from patients of the disease. [24] It is a member of the Oncology Research Information Exchange Network (ORIEN), a group of 16 institutions, as well as the Cooperative Human Tissue Network and the Applied Proteogenomics Organizational Learning and ...
Treatment may involve some combination of chemotherapy, radiation therapy, targeted therapy, and bone marrow transplant, with supportive and palliative care provided as needed. [3] [6] Certain types of leukemia may be managed with watchful waiting. [3] The success of treatment depends on the type of leukemia and the age of the person.
T-cell leukemia describes several different types of lymphoid leukemia which affect T cells. Types include: [1] Large granular lymphocytic leukemia; Adult T-cell leukemia/lymphoma; T-cell prolymphocytic leukemia; In practice, it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and they are often grouped together.
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