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Symptoms of colchicine overdose start 2 to 24 hours after the toxic dose has been ingested, and include burning in the mouth and throat, fever, vomiting, diarrhea, and abdominal pain. [26] This can cause hypovolemic shock due to extreme vascular damage and fluid loss through the gastrointestinal tract , which can be fatal.
Colchicine poisoning has been compared to arsenic poisoning; symptoms typically start two to five hours after a toxic dose has been ingested but may take up to 24 hours to appear, and include burning in the mouth and throat, fever, vomiting, diarrhea, abdominal pain, and kidney failure. Onset of multiple-system organ failure may occur within 24 ...
Macrolides, including azithromycin, should not be taken with colchicine as it may lead to colchicine toxicity. Symptoms of colchicine toxicity include gastrointestinal upset, fever, myalgia, pancytopenia, and organ failure. [33] [34]
Colchicum is lethally toxic due to its colchicine content and the leaves have been mistaken by foragers for those of Allium ursinum (ramsons or wild garlic), which they vaguely resemble. [13] [14] This plant (and colchicine itself) poses a particular threat to felines. The corms of meadow saffron contain the highest level of toxins, but all ...
This plant is poisonous, and toxic enough to cause human and animal fatalities if ingested. It has been used to commit murder, to achieve suicide, [11] and to kill animals. [7] Every part of the plant is poisonous, especially the tuberous rhizomes. As with other members of the Colchicaceae, this plant contains high levels of colchicine, a toxic ...
Azithromycin, should not be taken with colchicine as it may lead to colchicine toxicity. Symptoms of colchicine toxicity include gastrointestinal upset, fever, myalgia, pancytopenia, and organ failure. [45] [46]
Colchicine is an alternative for those unable to tolerate NSAIDs. [20] At high doses, side effects (primarily gastrointestinal upset) limit its usage. [98] At lower doses, which are still effective, it is well tolerated. [39] [99] [96] [97] Colchicine may interact with other commonly prescribed drugs, such as atorvastatin and erythromycin ...
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.