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Metallosis is the medical condition involving deposition and build-up of metal debris in the soft tissues of the body. [1]Metallosis has been known to occur when metallic components in medical implants, specifically joint replacements, abrade against one another. [1]
There are reports of cobalt toxicity with hip replacement, particularly metal-on-metal hip replacements, which are no longer in use. [49] [50] Use of metal-on-metal hip replacements from the 1970s was discontinued in the 1980s and 1990s, particularly after the discovery of aseptic lymphocyte-dominant vasculitis-associated lesions (ALVAL).
Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life. Some metals are toxic when they form poisonous soluble compounds. Certain metals have no biological role, i.e. are not essential minerals, or are toxic when in a certain form. [ 1 ]
Cobalt poisoning is intoxication caused by excessive levels of cobalt in the body. Cobalt is an essential element for health in animals in minute amounts as a component of vitamin B 12 . A deficiency of cobalt, which is very rare, is also potentially lethal, leading to pernicious anemia .
Either ingestion or faulty metabolic pathways can lead to metal toxicity (metal poisoning). Sources of toxic metals include cadmium from tobacco, arsenic from agriculture and mercury from volcanoes and forest fires. Nature, in the form of trees and plants, is able to trap many toxins and can bring abnormally high levels back into equilibrium.
The pelvic bone, also known as the innominate bone, is formed by three bones fused together: the ilium, ischium, and pubis. The musculature of the hip is divided into anterior hip muscles and posterior hip muscles. The major nerve supply that runs through the hip joint is the femoral nerve and the sciatic nerve. [16]
Iron deficiency anemia can intensify symptoms of fatigue and shortening of breath, and can cause cold sensitivity, hair loss, paleness to the skin and nail changes, says Cunningham. It has also ...
Although there is no cure, surgery is sometimes used to relieve symptoms. [18] Surgery may be necessary to treat misalignment of the hip (osteotomy of the pelvis or the collum femoris) and, in some cases, malformation (e.g., genu varum or genu valgum). [19] In some cases, total hip replacement may be necessary.