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Interneurons (also called internuncial neurons, association neurons, connector neurons, or intermediate neurons) are neurons that are not specifically motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits , enabling communication between sensory or motor neurons and the central nervous system (CNS). [ 2 ]
The theory offered a physiological explanation for the previously observed effect of psychology on pain perception. [10] In 1968, three years after the introduction of the gate control theory, Ronald Melzack concluded that pain is a multidimensional complex with numerous sensory, affective, cognitive, and evaluative components.
Some examples are: [citation needed] Basket cells, interneurons that form a dense plexus of terminals around the soma of target cells, found in the cortex and cerebellum; Betz cells, large motor neurons in primary motor cortex; Lugaro cells, interneurons of the cerebellum; Medium spiny neurons, most neurons in the corpus striatum
The singular example of a monosynaptic reflex is the patellar reflex. The next simplest reflex arc is a three-element chain, beginning with sensory neurons, which activate interneurons inside of the spinal cord, which then activate motor neurons. Some reflex responses, such as withdrawing the hand after touching a hot surface, are protective ...
Researchers observed changes in dorsal-ventral patterning, for example, zebrafish deficient in certain BMPs showed a loss of dorsal sensory neurons and an expansion of interneurons. [ 12 ] Shh secreted from the floor plate creates a gradient along the ventral neural tube.
The sensory input from the quadriceps also activates local interneurons that release the inhibitory neurotransmitter glycine onto motor neurons of antagonist muscles, blocking their stimulation (in this case the hamstring muscles). The relaxation of the opposing muscle facilitates (by not opposing) the extension of the lower leg.
Since the fast-spiking interneurons influence is located so closely to this critical gate between the dendrites and the soma, they can readily regulate the generation of an action potential. Additionally, other types of GABAergic interneurons make connections with the spiny neurons.
The knee-jerk reflex is an example of such a monosynaptic reflex. The most extensive input to α-MNs is from local interneurons, which are the most numerous type of neuron in the spinal cord. Among their many roles, interneurons synapse on α-MNs to create more complex reflex circuitry. One type of interneuron is the Renshaw cell.