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Nurse performing collagen induction therapy for scar reduction using a microneedle stamping device [ edit on Wikidata ] Collagen induction therapy ( CIT ), also known as microneedling , dermarolling , or skin needling , is a cosmetic procedure that involves repeatedly puncturing the skin with tiny, sterile needles (microneedling the skin).
This device received CE mark approval for sale outside the US after completing a wide clinical trial in Europe and South Africa. Multiple other inventions using the Z-Process include antigen reduced Z- meniscus, bone, articular cartilage, heart valves, collagen injection, soft tissue reconstruction devices, and other applications.
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Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. [3] In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and 6% by weight of skeletal muscle. [4] The fibroblast is the most common cell creating collagen in animals.