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ghrelin receptor: Stimulate appetite, secretion of growth hormone from anterior pituitary gland. 31 Glucagon: GCG Peptide: pancreas: alpha cells of Islets of Langerhans: Glucagon receptor → cAMP: glycogenolysis and gluconeogenesis in liver, activates lipase enzyme in adipose tissue cells, increases blood glucose level, inhibits storage of ...
2642 14527 Ensembl ENSG00000215644 ENSG00000288269 ENSMUSG00000025127 UniProt P47871 Q61606 RefSeq (mRNA) NM_000160 NM_008101 RefSeq (protein) NP_000151 NP_032127 Location (UCSC) Chr 17: 81.8 – 81.81 Mb Chr 11: 120.42 – 120.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and is considered to be the main catabolic hormone of the body. It is also used as a medication ...
The thyroid secretes thyroxine, the pituitary secretes growth hormone, the pineal secretes melatonin, the testis secretes testosterone, and the ovaries secrete estrogen and progesterone. [ 2 ] Glands that signal each other in sequence are often referred to as an axis, such as the hypothalamic–pituitary–adrenal axis .
Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood. The major glands of the endocrine system include the pineal gland , pituitary gland , pancreas , ovaries , testicles , thyroid gland , parathyroid gland , hypothalamus and adrenal glands .
Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein–coupled receptors. [5]
Hyperglycemia is one of the major adverse effects associated with glucagon receptor activation. Although glucagon receptors are densest in the liver, they also appear in other organs including the heart. Glucagon receptor agonists can increase heart rate, although cardiac risks may be mitigated by more tissue selective agonists with a ...
Insulin, which lowers blood sugar, and glucagon, which raises it, are the most well known of the hormones involved, but more recent discoveries of other glucoregulatory hormones have expanded the understanding of this process. The gland called pancreas secretes two hormones and they are primarily responsible to regulate glucose levels in blood. [1]