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Ciclopirox is a medication used for the treatment of moderate onychomycosis of fingernails and toenails, [3] and for the treatment of seborrheic dermatitis. [ 4 ] In 2022, it was the 247th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Ciclopirox olamine comes in different formulations, which can be used topically in a wide variety of fungal infections. [13] [14] Fungal skin infections Ciclopirox olamine cream or lotion is used to treat certain dermatophytosis such as tinea pedis, tinea cruris, and tinea corporis.
Ciclopirox (ciclopirox olamine) – a hydroxypyridone antifungal that interferes with active membrane transport, cell membrane integrity, and fungal respiratory processes. It is most useful against tinea versicolour .
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Regular use of an over-the-counter or prescription antifungal shampoo or cream is a common treatment. The topical antifungal medications ketoconazole and ciclopirox have the best evidence. [10] Ketoconazole should be used twice per week. [8] Shampoo or soap containing zinc pyrithione or selenium disulfide is also used. [8]
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Topical ciclopirox results in a cure in 6% to 9% of cases. [ 2 ] [ 31 ] Ciclopirox when used with terbinafine appears to be better than either agent alone. [ 2 ] Although eficonazole, P-3051 (ciclopirox 8% hydrolacquer), and tavaborole are effective at treating fungal infection of toenails, complete cure rates are low.
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