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The Nun Study of Aging and Alzheimer's Disease is a continuing longitudinal study, begun in 1986, to examine the onset of Alzheimer's disease. [1] [2] David Snowdon, an Epidemiologist and the founding Nun Study investigator, started the Nun Study at the University of Minnesota, later transferring the study to the University of Kentucky in 1990. [3]
By their usual definitions, childhood dementias always cause global neurocognitive decline. In some childhood dementia conditions the child's early development is indistinguishable from their healthy peers, then slows or plateaus before declining. In other childhood dementia disorders, early development may be slower than typical before declining.
Longitudinal research studies have recently conducted genetic analyses of centenarians and their offspring to identify protective factors against the negative effects of aging. In particular, the CETP gene is linked to prevention of cognitive decline and Alzheimer's disease. [ 90 ]
The Early Childhood Longitudinal Study (ECLS) program provides data about the development of children in the United States. [1] It is carried out by the Institute of Education Sciences. It provides data on children's status at birth and at various points thereafter.
A longitudinal study (or longitudinal survey, or panel study) is a research design that involves repeated observations of the same variables (e.g., people) over long periods of time (i.e., uses longitudinal data). It is often a type of observational study, although it can also be structured as longitudinal randomized experiment. [1]
The National Longitudinal Survey of Children and Youth (NLSCY) is a project of Statistics Canada which engages in the long-term study of children. The NLSCY is implemented by Statistics Canada and Human Resources and Social Development Canada, and charged with identifying and charting longer-term trends in Canadian youth. The survey tracks the ...
The Lothian birth-cohort studies [1] are two ongoing cohort studies which primarily involve research into how childhood intelligence relates to intelligence and health in old age. The Lothian Birth Cohort studies of 1921 and 1936 have, respectively, followed up Lothian -based participants in the Scottish Mental Surveys of 1932 and 1947 in old ...
Alzheimer's Disease Neuroimaging Initiative (ADNI) is a multisite study that aims to improve clinical trials for the prevention and treatment of Alzheimer's disease (AD). [1] This cooperative study combines expertise and funding from the private and public sector to study subjects with AD, as well as those who may develop AD and controls with ...