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Vibrio cholerae is a species of Gram-negative, facultative anaerobe and comma-shaped bacteria. [1] The bacteria naturally live in brackish or saltwater where they attach themselves easily to the chitin -containing shells of crabs, shrimp, and other shellfish.
The T6SS of Vibrio cholerae has a dual role, being able to target both bacterial and eukaryotic cells. [18] At least one substrate it secretes is specialized for eukaryotic cell-targeting, functioning by cross-linking the cytoskeleton protein actin. [19]
The Vibrionaceae are a family of Pseudomonadota given their own order, Vibrionales.Inhabitants of fresh or salt water, several species are pathogenic, including the type species Vibrio cholerae, which is the agent responsible for cholera.
Pathogenic Vibrio species include V. cholerae (the causative agent of cholera), V. parahaemolyticus, and V. vulnificus. V. cholerae is generally transmitted by contaminated water. [3] Pathogenic Vibrio species can cause foodborne illness (infection), usually associated with eating undercooked seafood. [18]
CAI-1 has no readily apparent recordable discovery date, but some of the earliest studies on autoinducers within and the quorum-sensing nature of V. cholerae was done by the Microbiology department of Harvard Medical school. [1] Prior to the study of V. cholerae, researchers obtained data from a close relative, Vibrio harveyi.
Vibrio cholerae, the species of bacteria that causes cholera, has over 200 serotypes, based on cell antigens. Only two of them have been observed to produce the potent enterotoxin that results in cholera: O1 and O139. [citation needed]
Cholera (/ ˈ k ɒ l ər ə /) is an infection of the small intestine by some strains of the bacterium Vibrio cholerae. [4] [3] Symptoms may range from none, to mild, to severe. [3]The classic symptom is large amounts of watery diarrhea lasting a few days. [2]
Vibrio cholerae str. El Tor El Tor is a particular strain of the bacterium Vibrio cholerae , the causative agent of cholera . Also known as V. cholerae biotype eltor, it has been the dominant strain in the seventh global cholera pandemic .