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Afoxolaner is the active ingredient of the veterinary medicinal products Nexgard, [3] Frontpro, and Nexgard Spectra (in combination with milbemycin oxime). [ 7 ] [ 16 ] [ 17 ] [ 18 ] They are indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies (8 weeks of age ...
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Nexgard Spectra (with afoxolaner) The drug has been used in marine reef aquaria to control parasitic Tegastidae copepod infestations on captive hard coral colonies. Other arthropod invertebrates will be killed by the treatment. [5] [6]
Since prevention is the most advanced way of fighting the disease, the veterinarians advise dog owners to get rid of ticks and fleas by using products like Advantix®, Frontline Plus®, Vectra 3D® or Bravecto®. Oral chewable options include Nexgard®, Simparica®, Credelio®, or Bravecto®. [20]
The isoxazoline class of insecticides was discovered by Nissan. They act by allosterically modulating GABA-gated chloride channels. (IRAC group 30).Four (Fluralaner, Lotilaner, Afoxolaner and Sarolaner) are used against fleas in dogs and cats, whereby foxalaner and sarolaner are only approved for dogs. [2]
Mange (/ ˈ m eɪ n dʒ /) is a type of skin disease caused by parasitic mites. [1] Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection, is sometimes reserved for pathological mite-infestation of nonhuman mammals.
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