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Other serious side effects include low blood potassium and myocarditis (inflammation of the heart). [3] It appears to be relatively safe in pregnancy. [4] There is a lipid formulation that has a lower risk of side effects. [4] It is in the polyene class of medications and works in part by interfering with the cell membrane of the fungus. [3] [4]
S100 calcium-binding protein B (S100B) is a protein of the S100 protein family. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a ...
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Intramuscular infusions are no longer widely used, as they can be painful and are more likely to cause reactions. People often experience adverse side effects from immunoglobulin infusions, including: swelling at the insertion site (common in SCIG) chills; headache; nausea (common in IVIG) fatigue (common in IVIG) muscle aches and pain, or ...
The most common side effects include hypersensitivity (allergic) reactions and infusion-related reactions. [ 10 ] Although Sotrovimab was used world-wide against SARS-CoV-2, including in the United States under an FDA emergency use authorization (EUA), the FDA canceled the EUA in April 2022 due to lack of efficacy against the Omicron variant.
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Cancer immunotherapy (immuno-oncotherapy) is the stimulation of the immune system to treat cancer, improving the immune system's natural ability to fight the disease. [1] It is an application of the fundamental research of cancer immunology (immuno-oncology) and a growing subspecialty of oncology.
The advantage of active monoclonal antibody therapy is the fact that the immune system will produce antibodies long-term, with only a short-term drug administration to induce this response. However, the immune response to certain antigens may be inadequate, especially in the elderly.