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The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.
Taking an example, the area under the curve y = x 2 over [0, 2] can be procedurally computed using Riemann's method. The interval [0, 2] is firstly divided into n subintervals, each of which is given a width of 2 n {\displaystyle {\tfrac {2}{n}}} ; these are the widths of the Riemann rectangles (hereafter "boxes").
Area under the curve. Add languages. Add links. Article; Talk; English. Read; Edit; View history; Tools. ... Text is available under the Creative Commons Attribution ...
A classification model (classifier or diagnosis [7]) is a mapping of instances between certain classes/groups.Because the classifier or diagnosis result can be an arbitrary real value (continuous output), the classifier boundary between classes must be determined by a threshold value (for instance, to determine whether a person has hypertension based on a blood pressure measure).
The blue area is under Ca area but not under Cb area. A U C = ∫ x = 0 1 R O C ( x ) d x {\displaystyle AUC=\int _{x=0}^{1}ROC(x)\ dx} The AUC is widely used, especially for comparing the performances of two (or more) binary classifiers: the classifier that achieves the highest AUC is deemed better.
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The usefulness of this heuristic especially depends on the question under consideration. In the empirical sciences , the so-called three-sigma rule of thumb (or 3 σ rule ) expresses a conventional heuristic that nearly all values are taken to lie within three standard deviations of the mean, and thus it is empirically useful to treat 99.7% ...
In qualitative terms, a line integral in vector calculus can be thought of as a measure of the total effect of a given tensor field along a given curve. For example, the line integral over a scalar field (rank 0 tensor) can be interpreted as the area under the field carved out by a particular curve.