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  2. Elevated alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Elevated_alpha-fetoprotein

    Like any elevated tumor marker, elevated AFP by itself is not diagnostic, only suggestive. Tumor markers are used primarily to monitor the result of a treatment (e.g. chemotherapy). If levels of AFP go down after treatment, the tumor is not growing. In the case of babies, after treatment AFP should go down faster than it would normally. A ...

  3. Hepatoblastoma - Wikipedia

    en.wikipedia.org/wiki/Hepatoblastoma

    The most common method of testing for hepatoblastoma is a blood test checking the alpha-fetoprotein level. Alpha-fetoprotein (AFP) is used as a biomarker to help determine the presence of liver cancer in children. At birth, infants have relatively high levels of AFP, which fall to normal adult levels by the second year of life.

  4. Alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Alpha-fetoprotein

    Very high AFP levels may be subject to hooking (see Tumor marker), which results in the level being reported significantly lower than the actual concentration. [29] This is important for analysis of a series of AFP tumor marker tests, e.g. in the context of post-treatment early surveillance of cancer survivors, where the rate of decrease of AFP ...

  5. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Alpha-fetoprotein (AFP) is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in hepatocellular ...

  6. Endodermal sinus tumor - Wikipedia

    en.wikipedia.org/wiki/Endodermal_sinus_tumor

    Diagnosis of EST in pregnant women and in infants is complicated by the extremely high levels of AFP in those two groups. Tumor surveillance by monitoring AFP requires accurate correction for gestational age in pregnant women, and age in infants. In pregnant women, this can be achieved simply by testing maternal serum AFP rather than tumor ...

  7. Malignant peripheral nerve sheath tumor - Wikipedia

    en.wikipedia.org/wiki/Malignant_peripheral_nerve...

    Symptoms may include: Swelling in the extremities (arms or legs), also called peripheral edema; the swelling often is painless. Difficulty in moving the extremity that has the tumor, including a limp. Soreness localized to the area of the tumor or in the extremity. Neurological symptoms. [3] Pain or discomfort: numbness, burning, or "pins and ...

  8. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    Myeloma cells produce monoclonal proteins of varying types, most commonly immunoglobulins (antibodies) and free light chains, resulting in abnormally high levels of these proteins in the blood. Depending on the size of these proteins, they may be excreted through the kidneys.

  9. Papillary thyroid cancer - Wikipedia

    en.wikipedia.org/wiki/Papillary_thyroid_cancer

    Post-operative complications at high-volume thyroid surgery centers with experienced surgeons are comparable to that of hemithyroidectomy. Arguments for hemithyroidectomy: Most patients have low-risk cancer with an excellent prognosis, with similar survival outcomes in low-risk patients who undergo total thyroidectomy versus hemithyroidectomy.

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