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Another translocation, involving chromosomes 11 and 22, has been found in a small number of people who have undergone cancer treatment. This chromosomal change is associated with the development of AML following chemotherapy for other forms of cancer. [citation needed] Mutations in the EP300 gene have been identified in several other types of ...
An example of modest stereoselectivity is the dehydrohalogenation of 2-iodobutane which yields 60% trans-2-butene and 20% cis-2-butene. [5] Since alkene geometric isomers are also classified as diastereomers, this reaction would also be called diastereoselective.
E-P147 includes most of the subclades found in E-M96.The two branches of E-P147 have different distributions; while the less common branch, Haplogroup E-M132, has more of a distribution within West Africa, the more common branch, E-P177, can be found widely distributed with high frequency throughout Africa and to a lesser extent in the Middle East and Europe.
E-M215 or E1b1b, formerly known as E3b, is a major human Y-chromosome DNA haplogroup.E-M215 has two basal branches, E-M35 and E-M281. E-M35 is primarily distributed in North Africa and the Horn of Africa, and occurs at moderate frequencies in the Middle East, Europe, and Southern Africa.
E-M132/E1a has been found in the remains of one Guanche (1/30) from the Canary Islands, and one Bimbape (1/16) from El Hierro that has been dated to the 10th century CE. [6]A man from the Koban culture (1/15) of the North Caucasus, which has been dated between the 9th century BCE and the 7th century BCE, carried paternal haplogroup E1a2a1b1b, as well as maternal haplogroup J1b1 or J1c.
Haplogroup E-P2, also known as E1b1, is a human Y-chromosome DNA haplogroup.E-P2 has two basal branches, E-V38 and E-M215.E-P2 had an ancient presence in the Levant; presently, it is primarily distributed in Africa where it may have originated, and occurs at lower frequencies in the Middle East and Europe.
Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a protein for degradation via a proteasome. This covalent bond of ubiquitin or ubiquitin-like proteins to targeted proteins is a major mechanism for regulating protein function in eukaryotic ...
E-M35, also known as E1b1b1-M35, is a human Y-chromosome DNA haplogroup.E-M35 has two basal branches, E-V68 and E-Z827.E-V68 and E-Z827 are primarily distributed in North Africa and the Horn of Africa, and occur at lower frequencies in the Middle East, Europe, and Southern Africa.