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Stephen M. Stahl, renowned academician in psychopharmacology, has stated resorting to a dynamic psychostimulant, in particular, d-amphetamine is the "classical augmentation strategy for treatment-refractory depression". [84] However, the use of stimulants in cases of treatment-resistant depression is relatively controversial. [85] [86]
Treatment guidelines from the National Institute of Health and Clinical Excellence [37] recommend against the use of SSRIs in this disorder. Those from the American Psychiatric Association note that SSRIs confer no advantage regarding weight gain, but that they may be used for the treatment of co-existing depression, anxiety, or OCD. [38]
This may be done to maximize effectiveness of a specific treatment, minimize possible side effects, or both. [ 3 ] [ 4 ] In the treatment of psychiatric conditions including bipolar depression , [ 5 ] [ 6 ] a form of chronotherapy combining intermittent sleep deprivation and morning bright light has shown efficacy and relative tolerability in a ...
Meta-analyses suggest that the combination of psychotherapy and antidepressant medications is more effective in treating mild and moderate forms of depression than either type of treatment alone. [27] Patients with severe symptoms may require outpatient treatment or hospitalization. [7] The treatment of a major depressive episode can be split ...
The response rate to sleep deprivation is generally agreed to be approximately 40-60%. A 2017 meta-analysis of 66 sleep studies with partial or total sleep deprivation in the treatment of depression found that the overall response rate (immediate relief of symptoms) to total sleep deprivation was 50.4% of individuals, and the response rate to partial sleep deprivation was 53.1% [3] In 2009, a ...
An individual taking their own radial pulse. The pulse is the rate at which the heart beats while pumping blood through the arteries, recorded as beats per minute (bpm). [11] It may also be called "heart rate". In addition to providing the heart rate, the pulse should also be evaluated for strength and obvious rhythm abnormalities. [11]
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