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  2. Titration curve - Wikipedia

    en.wikipedia.org/wiki/Titration_curve

    A typical titration curve of a diprotic acid, oxalic acid, titrated with a strong base, sodium hydroxide.Both equivalence points are visible. Titrations are often recorded on graphs called titration curves, which generally contain the volume of the titrant as the independent variable and the pH of the solution as the dependent variable (because it changes depending on the composition of the ...

  3. Equivalence point - Wikipedia

    en.wikipedia.org/wiki/Equivalence_point

    Coupled to high resolution electronics, the best thermometric titration systems can resolve temperatures to 10 −5 K. Sharp equivalence points have been obtained in titrations where the temperature change during the titration has been as little as 0.001K. The technique can be applied to essentially any chemical reaction in a fluid where there ...

  4. Acid–base titration - Wikipedia

    en.wikipedia.org/wiki/Acid–base_titration

    pH after the equivalence point; 1. The initial pH is approximated for a weak acid solution in water using the equation: [1] = ⁡ [+] where [+] is the initial concentration of the hydronium ion. 2. The pH before the equivalence point depends on the amount of weak acid remaining and the amount of conjugate base formed.

  5. Titration - Wikipedia

    en.wikipedia.org/wiki/Titration

    The equivalence point occurs between pH 8-10, indicating the solution is basic at the equivalence point and an indicator such as phenolphthalein would be appropriate. Titration curves corresponding to weak bases and strong acids are similarly behaved, with the solution being acidic at the equivalence point and indicators such as methyl orange ...

  6. Neutralization (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Neutralization_(chemistry)

    In a titration of a weak acid with a strong base the pH rises more steeply as the end-point is approached. At the end-point, the slope of the curve of pH with respect to amount of titrant is a maximum. Since the end-point occurs at pH greater than 7, the most suitable indicator to use is one, like phenolphthalein, that changes color at high pH. [2]

  7. Gran plot - Wikipedia

    en.wikipedia.org/wiki/Gran_plot

    For a strong acid-strong base titration monitored by pH, we have at any i'th point in the titration = [+] [] where K w is the water autoprotolysis constant.. If titrating an acid of initial volume and concentration [+] with base of concentration [], then at any i'th point in the titration with titrant volume ,

  8. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    From the titration of protonatable group, one can read the so-called pK a 1 ⁄ 2 which is equal to the pH value where the group is half-protonated (i.e. when 50% such groups would be protonated). The pK a 1 ⁄ 2 is equal to the Henderson–Hasselbalch pK a (pK HH a) if the titration curve follows the Henderson–Hasselbalch equation. [14]

  9. Buffer solution - Wikipedia

    en.wikipedia.org/wiki/Buffer_solution

    Buffer capacity falls to 33% of the maximum value at pH = pK a ± 1, to 10% at pH = pK a ± 1.5 and to 1% at pH = pK a ± 2. For this reason the most useful range is approximately p K a ± 1. When choosing a buffer for use at a specific pH, it should have a p K a value as close as possible to that pH.