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Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current United States Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. [1]
The FDA issued a final rule on changes to the facts panel on May 27, 2016. [5] The new values were published in the Federal Register. [6] The original deadline to be in compliance was July 28, 2018, but on May 4, 2018, the FDA released a final rule that extended the deadline to January 1, 2020, for manufacturers with $10 million or more in annual food sales, and by January 1, 2021, for ...
There is no evidence to indicate that intravenous ascorbic acid therapy can cure cancer. [33] [32] According to the U.S. Food and Drug Administration (FDA), high-dose vitamin C (such as intravenous ascorbic acid therapy) has not been approved as a treatment for cancer or any other medical condition. [2]
Tolerable upper intake levels (UL), to caution against excessive intake of nutrients (like vitamin A and selenium) that can be harmful in large amounts. This is the highest level of sustained daily nutrient consumption that is considered to be safe for, and cause no side effects in, 97.5% of healthy individuals in each life stage and sex group.
However, simian consumption does not indicate simian requirements. Merck's veterinary manual states that daily intake of vitamin C at 3–6 mg/kg prevents scurvy in non-human primates. [83] By way of comparison, across several countries, the recommended dietary intake for adult humans is in the range of 1–2 mg/kg.
In response to the proposed bill, many health food companies began lobbying the government to vote down the laws and told the public that the FDA would ban dietary supplements. [4] A notable advertisement [5] featured the actor Mel Gibson being raided and arrested by FDA agents because he was taking vitamin C supplements. [6]