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Glutathione (GSH, / ˌ ɡ l uː t ə ˈ θ aɪ oʊ n /) is an organic compound with the chemical formula HOCOCH(NH 2)CH 2 CH 2 CONHCH(CH 2 SH)CONHCH 2 COOH. It is an antioxidant in plants , animals , fungi , and some bacteria and archaea .
Humans naturally create glutathione in their cells. One of its main functions is combating oxidative stress—a condition that is caused by having an imbalance of antioxidants in the body. This ...
Glutathione peroxidase 2 is an intestinal and extracellular enzyme, while glutathione peroxidase 3 is extracellular, especially abundant in plasma. [4] So far, eight different isoforms of glutathione peroxidase (GPx1-8) have been identified in humans.
Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. [5] GPX4 is a phospholipid hydroperoxidase that protects cells against membrane lipid peroxidation .
Plus, glutathione side effects and dosages. Here, find the health benefits of glutathione, an antioxidant that helps make proteins in the body. Plus, glutathione side effects and dosages.
Human and yeast glutathione synthetases are homodimers, meaning they are composed of two identical subunits of itself non-covalently bound to each other. On the other hand, E. coli glutathione synthetase is a homotetramer. [3] Nevertheless, they are part of the ATP-grasp superfamily, which consists of 21 enzymes that contain an ATP-grasp fold. [7]