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Erythema toxicum neonatorum is a common, non-threatening rash in newborns. [ 1 ] [ 2 ] It appears in 40-70% of newborns within the first week of life, and it typically improves within 1–2 weeks. [ 2 ] [ 3 ] [ 4 ] It only occurs during the newborn period, but may appear slightly later in premature babies.
Erythema toxicum neonatorum, neonatal cephalic pustulosis, transient neonatal pustular melanosis, folliculitis, miliaria and milia are often ruled out before diagnosis. [4] [7] Some experts consider neonatal cephalic pustulosis (NCP) a form of neonatal acne while others do not. [5] NCP presents with facial papules and pustules but no comedones.
Erythema toxicum neonatorum; Transient neonatal pustular melanosis; Miliaria pustulosa; Infantile acropustulosis; Eosinophilic pustular folliculitis; Acne neonatorum (neonatal acne) Benign neonatal cephalic pustulosis (also called neonatal malasezzia furfur pustulosis) Infantile generalized pustular psoriasis
Transient neonatal pustular melanosis (TNPM), also known as pustular melanosis, is a type of neonatal pustular eruption that is a transient rash common in newborns.It is vesiculopustular rash made up of 1–3 mm fluid-filled lesions that rupture, leaving behind a collarette of scale and a brown macule. [3]
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Infantile acne is a self-limiting condition that resolves by itself within 6–12 months of occurrence or occasionally by ages 4–5 and does not require treatment in most cases but topical therapies can be used, especially in more severe cases.
It can be caused by infection, massage, electrical treatment, acne medication, allergies, exercise, solar radiation (), photosensitization, [3] acute radiation syndrome, mercury toxicity, blister agents, [4] niacin administration, [5] or waxing and tweezing of the hairs—any of which can cause the affected capillaries to dilate, resulting in redness.
Other skin conditions that may appear similar include erythema toxicum neonatorum, transient neonatal pustular melanosis, infantile acne, miliaria, infantile acropustulosis, and sucking blisters. [3] CNS disease may appear like bacterial or other viral meningitis's. [3]