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Most children older than 6 months of age who have acute otitis media do not benefit from treatment with antibiotics. If antibiotics are used, a narrow-spectrum antibiotic like amoxicillin is generally recommended, as broad-spectrum antibiotics may be associated with more adverse events.
In a post-marketing surveillance evaluating safety in 2006 children with acute otitis media treated with cefditoren (median daily dose: 10.0 mg/kg with a median total treatment period of 7 days), the incidence of adverse reactions was 1.79%, without unexpected or serious adverse drug reactions reported.
It was a retrospective study (2008–2010) and looked at 441 children who attended a Belgian hospital emergency department and had a throat swab taken. It concluded that the Centor criteria are ineffective in predicting the presence of Group A beta-haemolytic streptococcus (i.e. antibiotic treatment-worthy) on throat swab cultures in children.
Otitis media. Acute otitis media is an infection of the middle ear. More than 80% of children experience at least one episode of otitis media by age 3 years. [23] Acute otitis media is also most common in these first 3 years of life, though older children may also experience it. [19]
Recurrent acute otitis media: three ear infections in six months or four infections in a year. [1] [7] Chronic otitis media with persistent effusion for six months (one ear) or three months (both ears). [1] [7] Tympanostomy tubes should only be inserted in children with persistent effusion during an active episode of effusion. [1]
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. [5]
The most common aetiology of acute otitis externa is bacterial infection, [5] while chronic cases are often associated with underlying skin diseases such as eczema or psoriasis. [6] A third form, malignant otitis externa, or necrotising otitis externa, is a potentially life-threatening, invasive infection of the external auditory canal and ...
Erdosteine has shown benefits also in the treatment of chronic rhinosinusitis with nasal polyposis and Otitis Media Secretorica. [11] Pediatric population; Erdosteine was tested in pediatric patients with lower tract respiratory disorders, in association with ampicillin, demonstrating a high symptoms reduction. [12]