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Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate, including those with polycystic ovary syndrome. [5] It is taken by mouth . [ 5 ]
Clomiphene is initiated for use in patients with polycystic ovary syndrome, psychogenic amenorrhea, post-oral contraceptive amenorrhea, and secondary amenorrhea of unidentified cause. [14] Serum estrogen should be measured prior to therapy which rules out primary pituitary or ovarian failure , endometrial carcinoma , hyperprolactinaemia .
Clomiphene is a selective estrogen receptor modulator (SERM). [5] It is the most widely used fertility drug. [ 6 ] Other medications in this class include tamoxifen and raloxifene , although both are not as effective as clomiphene and are thus less widely used for fertility purposes. [ 7 ]
Compared to them, the mortality rate was 4% higher for those who took multivitamins daily and 9% higher for those who took them less often. Younger vitamin users had the highest risk.
Enclomifene (INN Tooltip International Nonproprietary Name), or enclomiphene (USAN Tooltip United States Adopted Name), a nonsteroidal selective estrogen receptor modulator of the triphenylethylene group, acts by antagonizing the estrogen receptor (ER) in the pituitary gland, which reduces negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis, thereby increasing gonadotropin ...
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The researchers discovered that people who took vitamin D had a 40% lower risk of developing dementia than those who didn’t take a supplement. They also had a 15% higher five-year survival rate.
Clomifene citrate (Clomid is a common brand name) is the medication which is most commonly used to treat anovulation. It is a selective estrogen-receptor modulator, affecting the hypothalamic–pituitary–gonadal axis to respond as if there was an estrogen deficit in the body, in effect increasing the production of follicle-stimulating hormone.